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Kookolo w’ekibumba

Bisangiddwa ku Wikipedia

Kkansa w'ekibumba, era amanyiddwa nga kkansa w-ekibumba (hepatic cancer), kkansa atandika mu kibumba.[1] Kkansa eyava mu kifo ekirala okudda mu kibumba, emanyiddwa nga metastasis y'ekibumba, etera okusaasaanira okusinga eyo etandika mu kibumba.[2] Obubonero bwa kkansa w'ekibumba buyinza okuzingiramu ekiwundu oba obulumi ku ludda olwa ddyo wansi w'olubuto, okuzimba kw'olubumba, olususu olwakala, okukosebwa amangu, okukendeera kw'obuzito n'obunafu.[1]

Liver cancer
Other namesHepatic cancer, primary hepatic malignancy, primary liver cancer, hepatoma
CT scan of a liver with cholangiocarcinoma
Medical specialtyOncology
ObuboneroLump or pain in the right side below the rib cage, swelling of the abdomen, yellowish skin, easy bruising, weight loss, weakness[1]
Usual onset55 to 65 years old[3]
CausesCirrhosis due to hepatitis B, hepatitis C, or alcohol, aflatoxin, non-alcoholic fatty liver disease, liver flukes[2][4]
Diagnostic methodBlood tests, medical imaging, tissue biopsy[1]
PreventionImmunization against hepatitis B, treating those infected with hepatitis B or C[2]
TreatmentSurgery, targeted therapy, radiation therapy[1]
PrognosisFive-year survival rates ~18% (US);[3] 40% (Japan)[5]
Frequency618,700 (point in time in 2015)[6]
Deaths782,000 (2018)[7]

Kkansa w'ekibumba, era amanyiddwa nga kkansa w-ekibumba (hepatic cancer), kkansa atandika mu kibumba.[1] Kkansa eyava mu kifo ekirala okudda mu kibumba, emanyiddwa nga metastasis y'ekibumba, etera okusaasaanira okusinga eyo etandika mu kibumba.[2] Obubonero bwa kkansa w'ekibumba buyinza okuzingiramu ekiwundu oba obulumi ku ludda olwa ddyo wansi w'olubuto, okuzimba kw'olubumba, olususu olwakala, okukosebwa amangu, okukendeera kw'obuzito n'obunafu.[1]

Ekisinga okuvaako kookolo w'ekibumba ye cirrhosis olw'obulwadde bwa hepatitis B, hepatitis C oba omwenge.[4] Ebirala ebivaako mulimu aflatoxin, obulwadde bw'ekibumba obutaliimu masavu n'obulwadde bw'ekibumba.[2] Ebika ebisinga okumanyibwa ye kookolo w’ekibumba (HCC), akola ebitundu 80% ku balwadde, ne kookolo w’ekibumba.[2] Ebika ebitali bya bulijjo mulimu ekizimba ekiyitibwa mucinous cystic neoplasm ne intraductal papillary biliary neoplasm.[2] Okuzuula obulwadde buno kuyinza okuwagirwa okukeberebwa omusaayi n'okukuba ebifaananyi by'abasawo, nga kukakasibwa n'okukeberebwa ebitundu by'omubiri.[1]

Kaweefube w'okuziyiza mulimu okugema obulwadde bw'ekibumba B n'okujjanjaba abo abalina obulwadde bw'ekibumba B oba C.[2] Okukebera kirungi mu abo abalina obulwadde bw'ekibumba obutawona.[2] Enkola z'obujjanjabi ziyinza okuli okulongoosa, obujjanjabi obugendereddwamu n'obujjanjabi obw'amasannyalaze.[1] Mu mbeera ezimu, ablation therapy, embolization therapy oba okusimbuliza ekibumba kiyinza okukozesebwa.[1] Ebizimba ebitonotono mu kibumba biyinza okugobererwa ennyo.[1]

Kookolo w’ekibumba asookerwako mu nsi yonna y’akwata ekifo eky’omukaaga mu kusinga okukwatibwa kookolo (6%) era y’akwata ekifo ekyokubiri mu kufa kookolo (9%).[2][8] Mu mwaka gwa 2018, gwali mu bantu 841,000 era ne guviirako abantu 782,000 okufa.[7] Mu mwaka gwa 2015, abantu 263,000 baafa kookolo w’ekibumba, 245,000 olw’omwenge ate 167,000 olw’obulwadde bw’ekibumba C.[9] Emiwendo mingi egya kookolo w’ekibumba gibaawo awali obulwadde bw’ekibumba B ne C, omuli Asia ne sub-Saharan Africa.[2] Abasajja batera okukosebwa HCC okusinga abakazi.[2] Okuzuula obulwadde businga kubeera mu abo ab’emyaka 55 okutuuka ku 65.[3] Omuwendo gw’abantu abawangaala mu myaka etaano guli 18.4 % mu Amerika,[3] ne 40.4% mu Japan.[5] Ekigambo "ekibumba" kiva mu Luyonaani hêpar, ekitegeeza "ekibumba".[10]

Ebiwandiiko ebikozesebwa

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  1. 1 2 3 4 5 6 7 8 9 10 11 "Adult Primary Liver Cancer Treatment (PDQ®)–Patient Version". NCI. 6 July 2016. Archived from the original on 2 October 2016. Retrieved 29 September 2016.
  2. 1 2 3 4 5 6 7 8 9 10 11 12 World Cancer Report 2014. World Health Organization. 2014. pp. Chapter 5.6. ISBN 978-9283204299.
  3. 1 2 3 4 "SEER Stat Fact Sheets: Liver and Intrahepatic Bile Duct Cancer". NCI. Archived from the original on 2017-07-28.
  4. 1 2 GBD 2013 Mortality and Causes of Death, Collaborators (17 December 2014). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013". Lancet. 385 (9963): 117–71. doi:10.1016/S0140-6736(14)61682-2. PMC 4340604. PMID 25530442. {{cite journal}}: |first= has generic name (help)
  5. 1 2 "がん診療連携拠点病院等院内がん登録生存率集計:[国立がん研究センター がん登録・統計]". ganjoho.jp. Archived from the original on 16 September 2015. Retrieved 2 February 2020.
  6. GBD 2015 Disease and Injury Incidence and Prevalence, Collaborators. (8 October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282. {{cite journal}}: |first1= has generic name (help)
  7. 1 2 Bray, F; Ferlay, J; Soerjomataram, I; Siegel, RL; Torre, LA; Jemal, A (November 2018). "Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries". CA: A Cancer Journal for Clinicians. 68 (6): 394–424. doi:10.3322/caac.21492. PMID 30207593. Archived from the original on 2021-04-17. Retrieved 2019-12-01.
  8. World Cancer Report 2014. World Health Organization. 2014. pp. Chapter 1.1. ISBN 978-9283204299.
  9. GBD 2015 Mortality and Causes of Death, Collaborators. (8 October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/s0140-6736(16)31012-1. PMC 5388903. PMID 27733281. {{cite journal}}: |first= has generic name (help)
  10. "Hepato- Etymology". dictionary.com. Archived from the original on 10 October 2015. Retrieved 24 October 2015.